Circadian rhythms are endogenous time-keeping mechanisms that regulate physiological processes in response to external ...

CD8 + T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic potential. For a long time, macrophages and foam cells were considered ...

For a long time, macrophages and foam cells were considered the principal agents in the formation of plaques. More recent studies, however, have focused on other immune system cells, CD8+ T cells ...

The same team of scientists also showed that KROS 101 increased the proliferation of helper and cytotoxic T cells (CD4+ and CD8+), while ... “Targeting M2 macrophage polarization: The anti ...

CD8 + T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic potential. Atherosclerosis is the most common cause of life-threatening ...

For β-cells, macrophage/DCs, and CD8 + T cells, the values correspond to log(# cells/# endocrine cells). For HLA-ABC, the mean HLA-ABC expression for each cell in the islet was computed and log ...

In vivo macrophage or T cell depletion and in vitro cell coculture ... immunosuppression status of the tumour microenvironment and activation of an antitumorous CD8 + T cell response. Conclusions In ...

on CD8 + TRM cells. The IL-10 Feedback Loop and Tumor Memory To examine the source of IL-10 within the tumor microenvironment (TME) after bacterial therapy, researchers found that tumor-associated ...

tumor-associated macrophages, and myeloid-derived suppressor cells. It also showed correlations with immune-active cells such as B cells, CD8 + T cells, and dendritic cells. Single-cell analysis ...