What is the normal expression pattern of MYC? How is this expression controlled in non-transformed cells? Two questions immediately arose: what are the agonists that regulate MYC expression and is ...
Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...
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