Though a complex interplay of genes, diet, and environment contribute, 90% of cases share one thing in common: leptin resistance. In lean individuals, fat cells produce the hormone leptin ...
Leptin works by telling your hypothalamus — the portion of your brain that regulates appetite — that you’re full. Leptin resistance occurs when the message to stop eating doesn’t reach ...
Researchers say study findings have important implications for our understanding of the pathogenesis of obesity and potential therapeutic applications.