As the researchers describe in a paper in Cell Metabolism, the drug rapamycin restores leptin sensitivity to diet-induced ...

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...

Friedman’s laboratory at the Rockefeller University cloned the leptin gene in 1994. “Before our research, the cause of obesity in diet-induced obese mice was unknown, leaving a critical gap in our ...

Abstract and Introduction Research Design and Methods Results Discussion References Finally, accelerated diabetes occurred in leptin-treated female mice only when leptin administration was started ...

As the researchers describe in a new paper in Cell Metabolism, the drug rapamycin restores leptin sensitivity to diet-induced obese mice, leading to significant loss of fat with only minimal ...

A new study led by University of Calgary professor Dr. Tuan Trang, PhD, may help to explain why there is an ...

Researchers say study findings have important implications for our understanding of the pathogenesis of obesity and potential therapeutic applications.

Clinical trials with r-Met-hu-leptin were also performed for the treatment of hypothalamic amenorrhea, where a 3-month administration resulted in the appearance of spontaneous menstrual cycles ...