Researchers say study findings have important implications for our understanding of the pathogenesis of obesity and potential therapeutic applications.

Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though ...

As the researchers describe in a paper in Cell Metabolism, the drug rapamycin restores leptin sensitivity to diet-induced obese mice, leading to significant loss of fat with only minimal effects ...

As the researchers describe in a new paper in Cell Metabolism, the drug rapamycin restores leptin sensitivity to diet-induced obese mice, leading to significant loss of fat with only minimal ...