Research reveals how exercise triggers the release of specialized myokines that regulate metabolism, build muscle, reduce ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout the world. Atherosclerosis, or the buildup of plaque in the ...

Specifically, Auletta highlights the emerging science in stem cell transplants and cell therapies, including treatments like chimeric antigen receptor (CAR) T-cell therapy. He also discussed topics ...

This indicates that GLP-1 receptor agonists lead to greater reduction in overall body fat than that in muscle mass, resulting in an overall body fat percentage decrease of around 4.5%.

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In the present study, we aimed to explore the relationship between the level of serum vitamin D and irisin concentrations in the older adults with sarcopenia. Conclusions: This study demonstrated that ...

A decrease in mucus and decline in the interactions of some peptides/hormones with their respective receptors also occurs. Red cells illustrate inflamed cells. (↑) Increase Secretion and Greater; (↓) ...

Researchers also found the receptors for irisin, a group of proteins called αV integrins, in fat and bone cells. “This is a pretty big discovery because in the past years, nobody has identified the ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...