Dysbiosis resulting in gut-microbiome alterations with reduced butyrate production are thought to disrupt intestinal immune homeostasis and promote complex immune disorders. However, whether and ...

Intestinal barrier is a functional entity separating the gut lumen from the inner host, and consisting of mechanical elements (mucus, epithelial layer), humoral elements (defensins, IgA ...

Intestinal histology of rhIGFBP-3 or vehicle-treated CF and WT mice. Mice received rhIGFBP-3 or vehicle daily for 4 wk, and intestinal tissue was harvested from 10-wk-old B6xBALB F2 CF mice after ...

Most ampullary carcinomas are adenocarcinomas, but the histology varies with tumors comprising sub-types including papillary, adenosquamous, mucinous, and adenocarcinomas. Recent studies helped ...

Patients with chronic gastroesophageal reflux disease can develop specialised intestinal metaplasia (SIM). This is a histological lesion that predisposes to adenocarcinoma of the oesophagus, and is ...

Opioid Use in Murine Model Results in Severe Gastric Pathology that May Be Attenuated by Proton Pump Inhibition. The American Journal of Pathology, 2022; DOI: 10.1016/j.ajpath.2022.04.005 ...

“Gastrointestinal lymphomas are a diverse group of diseases with variable prevalence,” says Lauren B. Smith, MD, Department of Pathology, University of Michigan, Ann Arbor, MI.