Unlike conventional approaches that primarily target incretin signaling, DOXA leverages multi-target mechanisms to synchronize metabolic and neurological pathways by acting on: Orexin Signaling ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a ...

Targeting mitochondrial retrograde signaling may therefore be promising in the treatment or prevention of metabolic disorders ...

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...

Introducing DOXA: A Multi-Target Innovation for Diabetes NLS is pioneering DOXA (Dual Orexin and Multi-Pathway Modulation), a next-generation therapeutic approach integrating orexin receptor ...

SINGAPORE - Train services resumed fully on the North East Line (NEL) on Feb 10 after some delays during the morning rush hour due to a signalling fault. Commuters had experienced up to a 30 ...

SINGAPORE: Morning commuters on Monday (Feb 10) were hit by a delay on the North-East Line (NEL) due to a signalling fault at Buangkok MRT station. The disruption lasted for over an hour ...

The line between Bolton and Manchester Oxford Road is currently blocked due a fault with a signalling system near Salford Crescent. Services between Manchester and Bolton and Manchester and Wigan ...