This phenomenon, known as the incretin effect in humans, suggests that insulin secretion is not solely triggered by elevated blood sugar levels. Instead, it involves a more complex interplay of ...

In humans, this phenomenon is known as the incretin effect,' explains Jan Ache. It suggests that insulin secretion is not simply controlled by the rise in blood sugar levels, but by more complex ...

In addition to being a runnable CLI tool, D2 can also be used to produce diagrams from Go programs. For examples, see ./docs/examples/lib. This blog post also demos a complete, runnable example of ...

The extent to which newer, incretin-based drugs for obesity improve disease outcomes via weight loss versus the direct effects of these drugs is the subject of intense interest. Although reductions in ...

Incretins are intestinal hormones secreted in response to nutrient entry into the gut, inducing insulin secretion and inhibiting glucagon release. While this response is diminished in individuals with ...

Thus, diet alone may have profound effects on β-cell function and incretin secretion. Considering the findings of these studies, it is evident that incretin hormones play a pivotal role in ...

Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210008, China ...

Bile acids (BAs) and incretins are gut hormones involved in digestion and absorption of fatty acids, and insulin secretion, respectively. In recent years BAs and incretins are increasingly recognized ...

We aimed to investigate whether the reduced incretin effect observed in patients with type 2 diabetes is a primary event in the pathogenesis of type 2 diabetes or a consequence of the diabetic state.

Here, we reconstituted soluble, monomeric α-syn secretion by the expression of DnaJ homolog subfamily C member 5 (DNAJC5) in HEK293T cells. DNAJC5 undergoes palmitoylation and anchors on the membrane.