This IgM was recombinantly expressed in serum containing CHO DUKX-B11 cells resulting in cell clones with a maximum specific productivity of 10 pg/cell/day compared to the IgG1 cell line which ... and ...

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Chen and colleagues describe mechanisms by which UBA7 and UBE2L6 form disulfide bonds, disrupting the ISG15 transfer cascade. As other similar structures are currently available, the authors further ...

You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters ...

The results established mechanisms by which UBA7 and UBE2L6 form disulfide bonds, disrupting the ISG15 transfer cascade. While the biochemical and structural experiments are largely convincing, the ...

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by inflammation and bone erosion. The exact mechanism of RA is still unknown, but various immune cytokines, signaling pathways and ...

1 Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China 2 Department of Ophthalmology, Chengdu First People’s Hospital/Chengdu Integrated TCM and Western Medicine Hospital, ...