Our cells harbor a DNA detector termed cGAS to inform the immune system of viral and bacterial infections, cell death, as ...

A conserved molecular pathway controlled by the proteins cGAS, STING and IRF3 can detect DNA outside of these compartments, and report it to the neighbouring and immune cells by secondary ...

A research led by Sergio P. Acebrón, Researcher Ikerbasque at the UPV/EHU, develops a key tool to visualize the immune response to abnormal DNA, opening new avenues for the treatment of diseases.

Cells contain a DNA sensor called cGAS, which alerts the immune system to viral and bacterial infections, cell death, and cancer-related transformations. A research team led by Ikerbasque Research ...

Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

Nuclear IRF3, along with NF-κB, induces the transcription of pro-inflammatory cytokines, contributing to the inflammatory response characteristic of MASLD/MASH. Additionally, dead cells can release ...

These families are both activated by signaling pathways originating from identical PRRs and IκB ... Notably, IRF7 and its closest relative, IRF3, play a critical role in regulating the type I ...

POTUS said the card, which is a premium version of a Green Card, will provide immigrants with “a pathway to citizenship.” U.S. President Donald Trump announced a new "Gold Card" that will be ...

A group of House Democrats are set to reintroduce legislation on Wednesday afternoon that would provide recipients of the Deferred Action for Childhood Arrivals (DACA) program a pathway to become ...