IHL-42X is designed to treat OSA by targeting its underlying pathophysiology. An oral fixed-dose combination of dronabinol and acetazolamide, IHL-42X is currently advancing through the RePOSA Phase ...

During these events, the oxygen content of fetal blood may decrease (hypoxemia), and the carbon dioxide or carbonic acid content of the fetal blood may increase (hypercapnia). Despite the adaptive ...

resulting in disruption of normal gas exchange (intermittent hypoxia and hypercapnia) and sleep fragmentation. [1] The clinical spectrum of obstructive sleep-disordered breathing (SDB) includes ...

Hypoxia or hypercapnia did not develop in any patient during or after the operation. All 12 patients received blood transfusions (Table 1). The mean age of the transfused blood was ten days.

Methods to characterize vasoreactivity to oxygen changes, particularly hypoxia, would provide important complementary information to established hypercapnia techniques. However, existing methods to ...

Hypoxia alone increased odds of mortality by ... This can then lead to rebound hypertension and increased brain swelling. Hypercapnia can also be harmful, causing brain arterial dilation and ...

When establishing the optimal gas concentrations in the setter room required to optimize the incubation process, the effects of hypoxia and hypercapnia on embryonic and fetal development need to be ...

Pediatric patients that received chest compressions for cardiac arrest faced a reduced likelihood for survival to hospital ...

The frequency, intensity, and extent of hypoxia are increasing in these ecosystems as well, where climate change amplifies the effects of eutrophication, leading to deoxygenation and extensive ...