One of the most significant abnormalities underlying type 2 diabetes is continued production of glucose by the liver (gluconeogenesis). Thus, understanding the mechanisms by which gluconeogenesis is ...
or animal models of shock indicate a close link between mitochondrial dysfunction and impaired gluconeogenesis (21). Finally, signs of hepatic failure have been described in patients with severe ...
and quantify rates of liver mitochondrial oxidation and gluconeogenesis as it happens in the body. Using this approach, they ...