New research identifies the liver protein PTPRD as a key regulator of metabolic liver disease. Reduced levels of PTPRD disrupt glucose and lipid metabolism, promote liver fat accumulation, and impair ...

Currently, more than 500 million people worldwide suffer from diabetes, and the number ... and fibrosis through the TGF-β/Smad3 signaling pathway, worsening DKD. The activation of the NLRP3 ...

Several lines of evidence link metabolic dysregulation to late-life neurodegenerative diseases. The altered glucose ...

Researchers are shedding new light on the link between diet and cancer growth—especially the way certain fats may fuel ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are ...

Scientific evidence suggests that by downregulating Grb2 expression, BP1001-A could help lower blood glucose level by affecting insulin signaling. Bio-Path is conducting preclinical studies to ...