developed a method to measure both CAG-repeat lengths and gene expression in individual brain ... expansions offers a new explanation for the selective neurodegeneration seen in Huntington ...

Researchers successfully use a nonviral, piggyBac transposon system to introduce a transgene into cynomolgus monkeys.

Alzheimer's Disease (AD) is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like ...

Bioinformatics and experimental validation have revealed 179 shared differentially expressed genes (DEGs) between chronic lymphocytic leukemia (CLL) and diffuse large B-cell lymphoma (DLBCL), ...

Only recently has the ribosome - one of the oldest molecular machines in evolutionary terms - been recognized as an active regulator of gene expression at the level of protein biosynthesis.

Japanese researchers used a nonviral piggyBac system to genetically modify cynomolgus monkeys, enabling more accurate disease ...

This variability underscores the need in future applications to carefully select promoters—the regulatory regions ...

A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with ...

This paper explores the potential of mitochondrial-associated programmed-cell-death (mtPCD) patterns as biomarkers for ...

Foghorn Therapeutics advances FHD-909 for SMARCA4 tumors, backed by Eli Lilly partnership. Read here to know why we are ...

NG-350A is a next generation, systemically administered immunotherapy designed to drive intratumoral expression of a CD40 agonist monoclonal antibody in both ...