Background: With the introduction of GEP analysis in Total Therapy 2 (TT2) and validation in Total Therapy 3 (TT3), GEP-defined high-risk, present in ∼15% of patients, has emerged as the dominant ...

Analysis on pre-Rx GEP on 22 pts via gene set analysis revealed several enriched genetic pathways comparing pCR with non-pCR pts. Specifically, the KEGG (Kyoto Encyclopedia of Genes and Genomes) ...

Review Article Published: 14 August 2012 Gene expression profiling in human neurodegenerative disease Johnathan Cooper-Knock, Janine Kirby, Laura Ferraiuolo, Paul R. Heath, Magnus Rattray & Pamela ...