Glucagon, a key hormone in the regulation of glucose homeostasis, acts as a counter-regulatory hormone to insulin by promoting hepatic glucose output. Under normal conditions, insulin and glucagon ...

inhibiting glucagon release, and promoting satiety. Dysregulated signaling of these receptors has been implicated in type 2 diabetes, obesity, and metabolic dysfunction-associated steatotic liver ...

STATE COLLEGE, PA, UNITED STATES, January 28, 2025 /EINPresswire.com/ -- INDIGO Biosciences, a premier provider of cell-based assay solutions, has introduced its new ...

GCGR Activation Graph GIPR Activation Graph GLP-1R Activation Graph A New Tool for Researchers Developing Dual- and Triple-Agonist Therapies for Obesity, Diabetes, and Other Metabolic Disorders STATE.

has introduced its new Glucagon Receptor (GCGR) Reporter Assay to accompany its already popular Glucagon-like Peptide-1 Receptor (GLP-1R) and Gastric Inhibitory Polypeptide Receptor (GIPR ...

1 Department of Hepatology, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Changchun, Jilin, China 2 Key Laboratory of Zoonosis Research, Ministry of ...

DD-01 is under clinical development by D&D Pharmatech and currently in Phase II for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). According to GlobalData, Phase II drugs for ...

The drug candidate is a next generation oxyntomodulin and targets glucagon like peptide 1 receptor (GLP1R) and glucagon receptor (GCGR). It is a new molecular entity (NME). Eli Lilly and Co (Lilly) is ...

Veiga-Fernandes and colleagues reported on their findings in Science, in a paper titled “Neuronal-ILC2 interactions regulate pancreatic glucagon and glucose homeostasis.” In their report the ...

and glucagon receptor (GCGR) dual agonist. OXM is a naturally-occurring gut hormone that activates GLP1R and GCGR, thereby decreasing food intake while increasing energy expenditure, thus ...

glucagon receptor (GCGR), and glucose-dependent insulinotropic polypeptide (GIP) receptor. It is believed that through these interactions, Retatrutide might influence glucose and lipid metabolism ...