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Frontiers21d
Protocatechualdehyde induced tumor suppressive autophagy through AMPK/ULK1 signaling pathway in gastric cancer
PCA significantly suppressed the growth of gastric cancer in the gastric cancer xenograft mouse model by activating key proteins related to the AMPK/ULK1 signaling pathway of autophagy. Conclusion: ...
Frontiers21d
Miltirone enhances the chemosensitivity of gastric cancer cells to cisplatin by suppressing the PI3K/AKT signaling pathway
Combination therapy of miltirone and cisplatin represents a novel potential treatment of gastric ... a pathway activator, and LY294002, an inhibitor, at a concentration of 10 μM. The results showed ...
C&EN25d
Canolol Alleviates Ethanol-Induced Gastric Ulcer by Inhibiting p38 MAPK/NF-κB/NLRP3 Pathway
Department of Nutriology, Oil Crops Research Institute, Chinese Academy of Agricultural Sciences, Wuhan 430062, China Hubei Key Laboratory of Lipid Chemistry and Nutrition, Oil Crops Research ...
SciELO26d
Chemoprotective effect of nimbolide against N-methyl-N-nitrosourea induced gastric cancer via alteration of apoptosis and NF-κB signaling pathway
The current investigation exhibited the anticancer effect of nimbolide against N-methyl-N-nitrosourea (MNU) induced gastric cancer (GC) rats via apoptosis and NF-κB signaling pathway. Male Swiss ...
appliedclinicaltrialsonline26d
Palatin Announces Results from Phase II Obesity Study of MC4R Bremelanotide Plus GLP-1/GIP Tirzepatide
Palatin has announced positive results from its BMT-801 Phase II clinical trial of co-administered melanocortin-4 receptor (MC4R) agonist bremelanotide plus glucagon like peptide-1/gastric inhibitory ...
The Pharma Letter27d
Palatin touts Phase II obesity study results
The company reported positive top-line data with co-administered melanocortin-4 receptor (MC4R) agonist bremelanotide plus glucagon like peptide-1/gastric inhibitory polypeptide (GLP-1/GIP) ...