Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The ...

G protein-coupled receptors (GPCRs) are integral membrane proteins with seven membrane-spanning helices. Upon binding to a ligand – which can range from small molecules like cyclic AMP to ...

Basic science researchers at the Johns Hopkins University School of Medicine are advancing heart health research by finding ...

Researchers at Leipzig University’s Faculty of Medicine and Shandong University in China have discovered a new mechanism that ...

Monash University researchers have revealed how the gut—and what we eat—regulates high blood pressure, opening the door to ...

Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Announcing a new article publication for BIO Integration journal.   Diabetes, a common metabolic condition, poses a substantial health burden worldwide. To revolutionize diabetes management, enhance ...

Researchers investigate the underlying mechanisms of endothelial insulin resistance involved in obesity-associated diabetes.

Researchers have developed a standardized numbering system for adhesion GPCRs, improving knowledge transfer and disease analysis. This AI-driven system, based on 14,000 modelled structures, ...

Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.