However, the mechanism by which heterotrimeric G proteins are activated by their ... are sophisticated allosteric machines with multiple signaling outputs. You have full access to this article ...

G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

Other signaling molecules must move much farther ... Membrane receptors fall into three major classes: G-protein-coupled receptors, ion channel receptors, and enzyme-linked receptors.

Venetia Zachariou, PhD, Edward Avedisian Professor and chair of pharmacology, physiology & biophysics at Boston University Chobanian & Avedisian School of Medicine, has received a Distinguished ...

Each cell in your body relies on precise communication with other cells to function properly. At the center of this process are the molecular switches that turn communication signals in the body on ...

A recent study published in Engineering delves into the complex mechanisms of drug addiction, highlighting the crucial role of astrocytic G protein-coupled receptors ... modulating astrocytic ...

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein ...