This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

Epigenetic rewiring characterization in IκBα-KO mESCs cultured in Serum/LIF. Related to Figure 4. A-D. Volcano plots from differential binding analysis of H3K4me3 (A), H3K27me3 (B), H3K4me1 (C) and ...

These studies define biological roles for Forkhead box a2 (FOXA2) and glands of the uterus in female reproduction and fertility. FOXA2 is a critical regulator of uterine gland development in the ...