Their study, published recently in Nature, focuses on what is known as the estrogen receptor, a protein linked in previous research to the development of roughly 70% of all breast tumors.

Hormone-receptor negative breast cancer, which includes estrogen receptor–negative (ERneg ... and the methionine pathway, ...

such as gases like nitrous oxide and steroid hormones like estrogen. Once a receptor protein receives a signal, it undergoes a conformational change, which in turn launches a series of biochemical ...

Protein–protein interaction networks are ... Native top-down proteomics reveals epidermal growth factor receptor–estrogen receptor-alpha (EGFR–ER) signaling crosstalk in breast cancer ...

a PROTAC protein degrader targeting the estrogen receptor protein for the treatment of patients with metastatic ER positive/HER2 negative breast cancer. The company was founded in February 2013 ...