Eculizumab and ravulizumab are complement C5 inhibitors ... Iptacopan, an oral monotherapy for PNH, has shown promising results. 5 Could you discuss its mechanism of action and comparative ...

Roche is taking on Alexion’s blockbuster Soliris (eculizumab), which was approved ... Enspryng has a different mechanism of action from Soliris too: Roche’s drug inhibits the IL-6 receptor ...

These patients broaden the autoimmune nodo-paranodopathy category and re-emphasise the usage of the term that pointing to the site of nerve injury reminds specific pathophysiological mechanisms ...

This article will review the mechanisms of activation of alternative, classical, and lectin pathways, the formation of C3 and C5 convertases, the action of anaphylatoxins ... of the anti-C5 blocking ...

The patient was finally diagnosed with MG by a significant decrement of Compound Muscle Action Potential in repetitive nerve ... such as rituximab, eculizumab, and batoclimab (24). Previous limited ...

AstraZeneca Pharma India received a Central Drugs Standard Control Organisation (CDSCO) permission to import, sale or distribute ‘Eculizumab’ concentrate solution for infusion 300 mg (10mg/ml).

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

The SARS-CoV-2 pandemic interrupted much respiratory research. Respiratory clinical academics joined colleagues in providing clinical care, and global research efforts were directed to finding new ...

Even though there are indications of the health-promoting and cell-protective properties of ergothioneine, the underlying mechanism of action was previously unknown. "Our analyses now finally ...

According to the exchange filing, regulatory authority Central Drugs Standard Control Organisation has allowed it to import pharmaceutical formulations of its drug Eculizumab for sale or for ...

Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the ...