Differin Acne Treatment Gel $ at Amazon Differin Acne Treatment Gel $ at Target 4.5-star average rating from 77,162 reviews on Amazon Learn more: Best treatments for teen acne ...

Treat mild acne with over-the-counter spot treatments that use benzoyl peroxide or salicylic acid, which are both proven to be effective in treating acne. And never try to pick or squeeze pimples.

Non-prescription acne products containing the active ingredients benzoyl peroxide or salicylic acid are of concern, the U.S. Food and Drug Administration says. (Shutterstock) ...