For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life.

As previously mentioned, the location at which a DNA strand begins to unwind into two ... and elongation are understood in the most basic sense, but many questions remain unanswered, particularly ...

Promoter sequences define the direction of transcription and indicate which DNA strand will be transcribed; this strand is known as the sense strand. Many eukaryotic genes have a conserved ...

Most dividing cells in the body have well-defined checkpoint mechanisms to sense and ... to measure the DNA repair capacity, repair protein expression profiles, and double-strand break levels ...

Researchers begin with a long strand of DNA, the scaffold ... "We just add these simple molecules to the system, and it's ready to sense something different," Guareschi says.

DNA helicases are essential during DNA replication because they separate double-stranded DNA into single strands, allowing each strand to be copied. Dr Taha Shahid, from the University of ...

This new research illustrates how small breaks in one strand of DNA can expand into a large single-stranded DNA gap that kills drug-resistant breast BRCA mutant cancer cells. The novel ...