Are there additional components/adaptors that contribute to lens development? Understanding the complexities of a pathway as critical as FGF signaling is necessary for future strategies to treating ...

Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. (Y.X., X.-Y.W., Z.-Y.H., H.Z., Z.-Y.Y ...

The G proteins, in turn, disengage with the GPCR and initiate the intracellular signaling pathways. The termination of GPCR activation (and signaling) is initiated by C-terminal phosphorylation of the ...

The cAMP signaling pathway is the ... the assembly and triggering of specific pathways to a defined area of the cell close to the substrate. Cyclic AMP has effects on a range of effector molecules ...

Chen’s discovery of cGAS, short for cyclic guanosine monophosphate-adenosine monophosphate ... As they dissected the signaling cascade of the MAVS pathway, Chen’s interest naturally turned to how DNA ...

Multiple signaling pathways converge to activate ERK, with different pathways being required for different stimulation patterns. To answer whether and how different temporal patterns select different ...

We have developed a fully synthetic lung surfactant preparation, based on designed analogues of surfactant proteins SP-B and SP-C, for treatment of respiratory distress syndrome in premature infants.

The cyclic AMP/protein kinase A (cAMP/PKA ... which dampens T-cell immune function through the cAMP/protein kinase A (PKA) signaling pathway. Indeed, the cAMP/type I PKA/Csk/Lck [lymphocyte-specific ...