The chemokine receptors CCR5 and CXCR4 are the two major coreceptors for HIV entry. Numerous efforts have been made to develop a new class of anti-HIV agents that target these coreceptors as an ...

In the assessment of 12-month price targets, analysts unveil insights for X4 Pharmaceuticals, presenting an average target of ...

G Protein-Coupled Receptors (GPCRs) in advancing GPCR-targeted therapies, including the use of agonists, antagonists, biased ...

Chemokines are a subclass of cytokines, a large family of small secreted proteins that communicate via G protein-coupled heptahelical chemokine receptors on the cell surface. Atrial fibrillation ...

RAPT Therapeutics, Inc.’s RAPT share price has dipped by 15.55%, which has investors questioning if this is right time to buy.

RAPT Therapeutics, Inc.’s RAPT share price has surged by 16.79%, which has investors questioning if this is right time to ...

CXCR3 and CXCR7 are chemokine receptors involved in cellular migration in physiological and pathophysiological context. Here, the authors present cryo-EM structures of CXCR3 in complex with small ...

The company's lead candidate, mavorixafor, is a first-in-class, small molecule antagonist of chemokine receptor CXCR4 being developed as a once-daily oral therapy. X4 believes that inhibition of ...

To this end, we employed flow cytometry-based screening to quantify the surface expression of major chemokine receptors and integrins. A significantly increased expression of CXCR3, CXCR4 ...

Equities researchers at HC Wainwright lifted their Q1 2025 EPS estimates for RAPT Therapeutics in a note issued to investors on Monday, March 10th. HC Wainwright analyst R. Selvaraju now expects that ...

Atypical chemokine receptor 1 on nucleated erythroid cells regulates haematopoiesis Nat Immunol 18:753-761, 2017. * Reviewed in F1000, IF: 21.5. Ulvmar MH, Braun A, Werth K, Kelay P, Hub E, Eller K, ...