New research uncovers that aging activates a new type of stem cell that rapidly produces fat cells, explaining why belly fat often expands in middle age.

Yes-associated protein (YAP) is a core effector molecule of the Hippo signaling pathway, which regulates transcription and controls cell proliferation and growth. However, the role of YAP in ...

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...

A novel drug combination targeting LSD1 and GSK3 shows promise in treating acute myeloid leukemia by promoting cell ...

The following is a summary of "ADORA2B promotes proliferation and migration in head and neck squamous cell carcinoma and is ...

This new review article published in Genes & Diseases sheds light on the pivotal role of fatty acid oxidation (FAO) in the ...

HT-KIT, a novel targeted therapy for GIST, demonstrated the ability to reduce tumor burden in humanized mouse models and induce tumor cell death.

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

In a nutshell Scientists discovered a new type of fat cell precursor (CP-A) that appears specifically during middle age, ...

"The proliferation of progenitor cells in response to injury ... of interacting genes called the Hippo pathway, which serve as a "stop growing" signal that the lab has shown to inhibit cell ...