Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.

New research uncovers that aging activates a new type of stem cell that rapidly produces fat cells, explaining why belly fat often expands in middle age.

The Wnt signaling pathway is a conserved network that regulates cell proliferation, differentiation, and migration. It ...

CD8 + T cells accumulate in atherosclerotic plaques. LMU researchers identify a crucial signaling pathway—with therapeutic ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

Yes-associated protein (YAP) is a core effector molecule of the Hippo signaling pathway, which regulates transcription and controls cell proliferation and growth. However, the role of YAP in ...