Researchers have identified a key pathway that links how neurons ... Zent et al, Synapse-to-nucleus ERK-CREB transcriptional signaling requires dendrite-to-soma Ca2+propagation mediated by L ...
Figure 1 TLR signaling pathway in innate immune cells ... The activation of these MAPKs leads to some important transcription factor activations, such as CREB, AP1. These transcription factors ...
We demonstrated that R1 is a promising compound that exerts neuroprotective and proneurogenic effects, possibly via the activation of BDNF/Akt/CREB signaling. These findings offer insight into ...
The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...
Scientists have uncovered a crucial pathway that links brain cell activity to the activation of genes responsible for ...
the mechanisms of action and patterns of interaction of these factors remain controversial. This article summarizes some of the known aspects of signaling pathways involved in apoptosis.
7 refine our understanding of the signaling effects of oncogenic KRAS. Rather than activating multiple effectors, mutant KRAS signals preferentially through the RAF–MEK–ERK pathway ...
Researchers have identified a key pathway that links how neurons send ... This research focuses on the cAMP-response element binding protein (CREB), a transcription factor known to regulate ...
Researchers have identified a key pathway that links how neurons send ... This research focuses on the cAMP-response element binding protein (CREB), a transcription factor known to regulate ...
The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...
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