CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

“Deep B-cell depletion ... Dren has another antibody in development in the form of DR-01, which is designed to selectively deplete cytotoxic cells such as autoreactive CD8 T cells.

therapy showed that CDK9 enhances CD8 + T cell function during ICB treatment. Additionally, HCC tumors with high HDAC2-AS2 expression were found to benefit more from PD-1 antibody therapy.

Depletion of the infiltrating neutrophils using a neutrophil-specific antibody in SM16-treated mice significantly reduced the antitumour effect of SM16, suggesting that tumour-associated ...