Here, we reveal crosstalk between ischemic penumbral neurons and endothelial cells (ECs) mediated by circular RNA originating ... surgery. Prussian blue staining was performed to detect iron in brain ...

For solid tumors, the survival, proliferation, and invasion of cancer cells rely on surrounding blood vessels to provide nutrients and oxygen. Cancer cells can increase the synthesis and secretion of ...

This results in increased endothelial cell ... and the cells were cultured with conditioned medium (CM). Six hours later, the cells were incubated with EdU in CM for 4 hours, followed by fixation and ...

Methods PEDF and Cav-1 expression in fibroblasts and endothelial cells ... anti-CD31, rabbit polyclonal anti-α-smooth muscle actin (SMA) (Abcam, UK) and a rabbit polyclonal anti-Cav-1 antibody (Santa ...

A protein that stops cells from dividing in response to damage or stress could be a new biomarker or therapeutic target for ...

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

In addition, distal pulmonary capillaries were preserved in the Piezo1-knockout mice, associated with a lower number of senescent endothelial cells. This study provides evidence that Piezo1 expressed ...

*Corresponding Author: Per Karlsson, Department of Oncology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg 40530, Sweden. E-mail: [email protected] Clin ...

It's also known as urothelial carcinoma because it starts in the cells that line the bladder, known as urothelial cells. These cells also line other parts of the urinary tract, such as the urethra ...

Our data provide novel insights into the mechanisms associated with secondary organ injury in arthritis, revealing tissue-specific alterations in cell types and numbers. Moreover, they provide ...