BMJ29d
Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression
Methods CD4+ and CD8+ T cells were investigated in 25 enthesis samples using immunofluorescence, cytometrically, bulk RNAseq and quantitative real-time PCR following anti-CD3/CD28 bead stimulation to ...
C&EN29d
Carrier-Free Nanocombo-Sensitized Photoimmunotherapy via Activation of α2-Adrenergic Receptors
After 48 h of coculture, the cells were collected, stained with antimouse CD3, antimouse CD4 ... To study the role of ICD in vitro, cells were subjected to immunofluorescence staining after different ...
eLife22d
Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma
The accuracy and clarity have been improved from the previous version, and additional immunofluorescence supporting the existence ... half of C4 is EPCAM+/CD3-, the other half EPCAM-/CD3+). These ...
eLife15d
Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice
Figure 4. B cell follicles in HIS mice. (A) H&E staining and immunofluorescence performed for CD20, CD3, and PNA in serial tissue sections of spleen from HIS mice with mouse vs human thymus at <20W, ...
Frontiers29d
A Modified Hyaluronic Acid–Based Dissolving Microneedle Loaded With Daphnetin Improved the Treatment of Psoriasis
For immunofluorescence staining ... The antibody used is described as follows: CD3 (BD Bioscience, United States); Vγ4 (BD Bioscience, United States); and IL-17 (BD Bioscience, United States). Human ...
The Boston Globe7d
Treatment for traumatic brain injury could come in the form of a nasal spray drug, study says
A nasal spray, referred to as nasal anti-CD3, could be the first FDA-approved treatment for traumatic brain injury, or TBI, that can be easily administered with no serious side effects ...
Medical Xpress8d
High-salt diet linked to depression: Protein IL-17A plays key role in mice study
Get Instant Summarized Text (Gist) A high-salt diet induces depression-like symptoms in mice by increasing the production of the protein IL-17A, which is linked to depression in humans. Gamma ...
ahajournals.org6d
AX-024 Inhibits Antigen-Specific T-Cell Response and Improves Intracerebral Hemorrhage Outcomes in Mice
Shuai Chen, MD https://orcid.org/0009-0007-8628-4313 Department of Neurology, The People’s Hospital of Zhengzhou University and Henan Provincial People’s Hospital ...
gut.bmj16d
High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity
Additionally, functional, transcriptional and spatial analyses of tumour-infiltrating lymphocytes were performed by flow cytometry, single-cell RNA-sequencing and multispectral immunofluorescence.