A seminal study has uncovered a new genetic cause of neurodevelopmental disorders (NDDs). The discovery offers both closure and hope to potentially thousands of families worldwide who have long been ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

In the years since the consensus statement was published, however, the evidence for each of these A.D.H.D. biomarkers has faltered. Attempts to replicate the studies that showed differences in brain ...

A team of over 150 scientists has achieved what once seemed impossible: a complete wiring and activity map of a tiny section of a mammalian brain. This feat, part of the MICrONS Project, rivals the ...

An estimated 18,000 people in the United States annually suffer from new injuries to their spinal cords. Unfortunately for ...

A recent paper links CAG repeat expansion with widespread RNA changes, especially in brain cells vulnerable to HD. “Knocking ...

The original PROOF-HD trial of pridopidine was negative, but a new analysis showed it has clinically meaningful effects in ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve ... The scientists found ...

New research suggests the adult brain can be convinced to grow new neurons to replace those lost in Huntington’s disease. The ...

Using a piece of that mouse’s brain about the size of a poppy seed, the researchers identified those neurons and traced how ...