With a brand new Amazing Spider-Man #1, a new Sinister Six can't be far behind. But which of Spider-Man's villainous foes ...

In Marvel's Spider-Man Multiverse, four versions of Peter Parker have donned a superhero costume to fight evil. Over two decades, fans have witnessed some of the best on-screen villains in this ...

Unlike many of Spider-Man's great villains, Otto Octavius dies a hero. Sandman is one of three antagonists in Spider-Man 3. At the beginning of the movie, Flint (Thomas Haden Church) is a human ...

But the interesting dynamic here would be a mystery that Spider-Man would have to uncover. It could be a superhero detective story, like a brighter version of a Batman tale. Finally, the Black Cat ...

In Sony's first official poster for Spider-Man: No Way Home, some of the web slinger's most iconic villains return, including Alfred Molina reprising his role as Doc Ock from 2004's Spider-Man 2 ...