Hypertension (high blood pressure) is a debilitating condition and a major cause of premature death worldwide. Chronic stress plays a significant role, but the underlying mechanism involving ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

Biosynthesis is the generation of natural products through enzymatic reactions, as in cellular metabolism. Successive enzymatic reactions by a number of enzymes are generally required to achieve a ...

As part of The Wistar Institute's Melanoma Research Center, the Villanueva lab pursues new ways to overcome the challenge of melanoma drug resistance. In this paper, the group took aim at melanomas ...

Figure 1. Schematic illustration of the biosynthesis of lycopodium alkaloids. Biosynthetic pathway of huperzine A (HupA). PtLDC, lycine decarboxylase; PtCAO, copper amine oxidase; PtPKS, piperidyl ...

Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Key Laboratory of Marine Materia Medica, Innovation Academy of South China Sea Ecology and Environmental Engineering, South China ...

Importantly, they are members of the human gastrointestinal microbial population, contributing to the metabolism of dietary and host secreted molecules found in this environment. The role of the ...

Metabolism often flies under the radar when designing a fat loss transformation program. A balanced 30-minute training session can boost your metabolism for up to 14 hours, which can be a game-changer ...

Moscot is a cell-mapping framework based on the concept of optimal transport. It can analyse large-scale single-cell data, enabling mapping of the developmental trajectories of individual cells in ...