Furthermore, our exploration unveiled that SST orchestrates the modulation of T-cell responses and metabolism through somatostatin receptor 3 (SSTR3) mediated activation of glycogen synthase kinase 3 ...

1 Division of Endocrinology, Diabetes & Metabolism, Assistant Professor ... Glucocorticoid receptor antagonists (mifepristone) and somatostatin receptor antagonists (pasireotide) represent ...

The secretion is regulated by two hypothalamic peptides, growth hormone releasing hormone, which stimulates hGH secretion, and somatostatin ... The effects of GH on the metabolism are so widespread ...

Therefore, abnormal lipid metabolism could inhibit the growth and decrease the ... factor (IGF), leptin (LEP), pancreatic polypeptide (PP), peptide YY (PYY), and somatostatin (SS) were measured using ...

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical ...

Now researchers from The Rockefeller University have unearthed intriguing genetic evidence: a protein variant found only in humans that may have helped shape the emergence of spoken language.

Somatostatin analogues are medicines that stop your body from making too many hormones. Some neuroendocrine tumours (NETs) make large amounts of hormones. This can cause symptoms. Somatostatin ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

Biosynthesis is the generation of natural products through enzymatic reactions, as in cellular metabolism. Successive enzymatic reactions by a number of enzymes are generally required to achieve a ...

Molecular imaging, including somatostatin receptor scintigraphy but more so PET with specific tracers, such as C 11-5HTP or Ga 68-DOTA octreotate, will improve staging and follow-up of therapy in ...

Moscot is a cell-mapping framework based on the concept of optimal transport. It can analyse large-scale single-cell data, enabling mapping of the developmental trajectories of individual cells in ...