Early clearance of measurable residual disease (MRD) after induction therapy in patients with acute myeloid leukemia (AML) is associated with significantly better relapse-free survival (RFS) than ...

The basophil activation test (BAT) is not a primary diagnostic tool; it is a test complementary to the skin test and quantification of allergen-specific IgE. The BAT is currently mostly applied in ...

Human basophils, first identified over 140 years ago, account for just 0.5-1% of circulating leukocytes. While this scarcity long hampered basophil studies, innovations during the past 30 years, ...

After hours: March 20 at 7:49:50 PM EDT Loading Chart for BEAM ...

Mar. 17, 2025 — A new study reveals a novel approach to mitigating tissue damage caused by Streptococcus pyogenes, the flesh-eating bacterium responsible for severe infections such as ...

Patients with acute promyelocytic leukemia (APL) often present with potentially life-threatening hemorrhagic diathesis. The underlying pathomechanisms of APL-associated coagulopathy are complex.

They found that small molecule inhibitors of the enzyme Bruton’s tyrosine kinase (BTK), which is a key component of the IgE signaling pathway, completely suppress IgE-mediated human mast cell and ...

Division of Hematologic Malignancies and Cellular Therapeutics, University of Kansas Medical Center, Westwood, KS, USA The recent clinical successes of immunotherapy, as a result of a broader and more ...