The Namodenoson oral drug is well positioned in the field of anti-obesity agents due to its activity and favorable safety ...

Can-Fite BioPharma Ltd. (NYSE: CANF), shares barely budged Monday as the biotechnology company advancing a pipeline of proprietary small molecule drugs that address oncological and inflammatory ...

Mitochondria are interconnected with the endocrine system, particularly in regulating hormones like leptin and adiponectin. Leptin controls hunger and energy balance, while adiponectin enhances ...

Higher adiponectin levels were linked to improved metabolic health transitions and reduced diabetes risk across 6 years. Higher adiponectin levels are associated with improved metabolic health ...

In a Phase IIa study for MASH, subjects treated with the drug experienced a 2.3% weight loss over three months, accompanied by a significant increase in serum adiponectin levels. The drug’s ...

Many studies have shown that small-molecule natural products can improve renal function and ameliorate kidney disease progression. This review summarizes the nephroprotective effects of small-molecule ...

Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of diabetes. Microvascular endothelial cells are thought to be the major targets of hyperglycemic injury. In ...

From the Center for Systems Biology (W.C.P., M.N., F.K.S.), Massachusetts General Hospital and Harvard Medical School, Boston. From the Center for Systems Biology (W ...

and adiponectin. Targeted population and its characteristics; age, sex, ethnicity, disease prevalence in group, location and the distance from equator, if possible; Intervention outcomes: this will ...