Users say they feel relief from burning feet, numb fingers, nerve zaps, and leg cramps within weeks. More impressively, many ...

It’s our favourite caffeine fix, but your morning pick-me-up could be impacting your body in unexpected ways, from hair and ...

Arialief offers a satisfaction guarantee, allowing customers to try the product risk-free. If users do not experience the ...

ROS, Reactive Oxygen Species; ATP, Adenosine Triphosphate ... nAChR, Nicotinic acetylcholine receptor; MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Ca, calcium. However, it is critical to ...

We found that DA-LTP is absent in GluA1 knock-out mice and that it requires calcium-permeable AMPA receptors ... D1 and D5 dopamine receptors are known to activate ACs, which increase cyclic adenosine ...

McGill University researchers have demonstrated that AMPA receptors (AMPARs), which mediate fast excitatory neurotransmission ...

GluA2, one of the primary subunits of AMPARs, has long been thought to prevent calcium permeability when included in the receptor complex. Results indicate that the R607E and R607G missense ...

A new study by McGill University researchers yields insights into how the disruption of calcium transport in the brain is linked to autism and intellectual disability.

The AMPA group of brain receptors have mostly been assumed to be calcium impermeable and so were not thought to contribute to the calcium-dependent mechanisms underlying learning and memory.

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.