Lyophilization (freeze-drying) is commonly utilized to support peptide stability. Removing water from peptide solutions might significantly reduce hydrolysis and deamidation rates. Lyophilized ...

and the presence of specific amino acid residues. Hydrolysis, or peptide bond cleavage via reaction with water, is theorized to be a primary degradation mechanism, particularly in aqueous solutions.

Vapourtec’s R-Series flow chemistry system, equipped with a UV-150 photochemical reactor, has been cited in research by scientists* at Novo Nordisk in the C-terminal a-amination of peptides and ...

Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis). Proteases can also remove protein post ...

acid-base equilibria (including multi stage ionisation) and ionisation constants, ionisation of water. PH scale, common ion effect, hydrolysis of salts and PH of their solutions, the solubility of ...

During early elongation steps, Ami does not compromise EF-Tu-dependent A-site binding or peptide bond formation. On the other hand ... with EF-G (magenta) amino acids (yellow), providing resistance to ...

A breakthrough by researchers at The University of Manchester sheds light on one of nature's most elusive forces, with wide-reaching implications for medicine, energy, climate modeling and more. The ...

Birmingham scientists have shown that a sequence of just three amino acids may reduce the severity of psoriasis when applied ...

Propane dehydrogenation (PDH) reaction is a highly endothermic reaction, typically requiring temperatures above 600°C in conventional thermo-catalysis. However, elevated temperatures lead to ...

Antimicrobial resistance is a global issue, making the search for a new generation of antibiotics imperative. Scientists ...