Purpose: The toxicology of oral antidiabetic agents is reviewed. Summary: Type 2 diabetes mellitus is increasing to near epidemic proportions, with a reported 190 million patients worldwide. Use ...

Acarbose and miglitol, the only α-glucosidase inhibitors available in the United States, competitively and reversibly inhibit glucoamylase, sucrase, maltase, and isomaltase in the brush border of ...