AceLink is advancing a small-molecule treatment option for Fabry disease, which could provide a more convenient alternative ...

Obesity significantly impacts cardiovascular health, increasing risks such as left ventricular hypertrophy, atherosclerosis, ...

Background Early heart failure (HF) diagnosis is crucial to ensure that optimal guideline-directed medical therapy (GDMT) is ...

Study reveals how the JAK inhibitor lowers ACE2 expression ... and entry into host cells by binding to the angiotensin converting enzyme (ACE2) receptor. The expression of ACE2, which is present ...

This prospective case-control study included 85 patients with lung involvement related to the COVID-19 virus and a group of ...

Angiotensin-converting enzyme inhibitors induce cough ... Mouth breathing, dry air, and low water permeation promote inflammation, and activate neural pathways, by osmotic stresses acting on airway ...

More recently, pharmacological agents targeting other neurohormonal pathways have demonstrated further opportunities ... The four pillars consist of ACE inhibitors/sacubitril–valsartan, beta-blockers, ...

(Figure 5: Shannon: SMD = -0.33; 95%CI: -0.69 to 0.03; P < Q19 0.001; Simpson: SMD = -0.36; 95%CI: -0.68 to -0.05; P < 0.001; ACE: SMD = -0.25 ... there is evidence to suggest that TNF inhibitors may ...

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.

In a video interview, William K. Oh, MD, director of precision medicine at Yale Cancer Center and Smilow Cancer Hospital discusses the latest breakthroughs in advanced prostate cancer treatment.