Cardiovascular diseases are the world's leading cause of death, and high blood pressure, or hypertension, affects more than 1 ...

High blood pressure, or hypertension, affects more than 1 billion people globally. Many of them are prescribed angiotensin-converting enzyme inhibitors—better known as ACE-1 inhibitors (ACEIs)—and/or ...

The RAS pathway regulates blood pressure by triggering ... which ACE then converts into angiotensin II, a vasoconstrictor. ACE inhibitors and ARBs lower blood pressure by acting on different ...

IgA nephropathy (IgAN) is an autoimmune disorder that affects the kidneys by impairing the filtration function of the small ...

Discover the symptoms, causes and treatments for hereditary angioedema, a rare genetic disorder causing severe swelling that ...

In particular, the mechanistic target of rapamycin (mTOR) pathway has been tied to multiple ... anti-aging drugs like metformin, aspirin, ACE inhibitors, angiotensin receptor blockers, and PDE5 ...

Genprex, Inc. ("Genprex" or the "Company") , a clinical-stage gene therapy company focused on developing life-changing therapies for patients with cancer and diabetes, today announced that its ...

More recently, pharmacological agents targeting other neurohormonal pathways have demonstrated further opportunities ... The four pillars consist of ACE inhibitors/sacubitril–valsartan, beta-blockers, ...

Angiotensin-converting enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs) are recommended widely as first-line treatments for hypertension in patients with diabetic or nondiabetic ...