You can develop diabetes insipidus if you have a deficiency of or resistance to antidiuretic hormone (ADH), also known as vasopressin, a hormone responsible for keeping water levels balanced in ...

Tolvaptan is a vasopressin receptor antagonist. Vasopressin (a.k.a. ADH or antidiuretic hormone) helps to regulate water retention by absorbing water in the collecting ducts of the nephron.