and GLP-1 agonists such as semaglutide (in people with both HFpEF and obesity). These drugs help people lose weight and have also been shown to reduce hospitalization for heart failure.

Opko Health and Entera Bio have formalized their partnership as the biotechs prepare to take the first orally administered dual agonist glucagonlike-peptide 1 (GLP-1)/glucagon peptide into the clinic.

Pfiz­er’s pipeline pri­or­i­ti­za­tion has now turned to a STING ag­o­nist, with an ear­ly-stage study ter­mi­na­tion of the as­set, a spokesper­son con­firmed to End­points News ...

In this case, it is believed that GLP-1 agonists act on the receptors in these regions to suppress addiction. Most of the research in this area has focused specifically on alcohol addiction, and ...

More research is needed to understand the effects of Ozempic and other GLP-1 agonists on people with eating disorders, including the potential of the drugs to treat binge eating disorder.

But in March 2024, a thyroid hormone receptor–beta (THR-beta) agonist called resmetirom (Rezdiffra) received accelerated approval by the U.S. Food and Drug Administration (FDA). Accelerated ...

The medicines — known as dopamine agonists — interact with parts of the brain that control movement, helping to ease restless leg syndrome, which is thought to impact one in 10 people in the UK.

Patients taking dopamine agonists say the drugs have triggered uncontrollable impulses, including flashing, sex addiction and even pedophilia — leaving them struggling with feelings of shame and ...