reducing food intake and having trophic effects on the pancreatic islet cells. [9] These incretin hormones have been implicated recently in the pathogenesis of Type 2 diabetes. GLP-1 is ...
New entrants: incretin-based therapies ... effectiveness over time, and side effects limit compliance. Beyond the GLP1 analogues and DPP4 inhibitors, the diabetes pipeline includes compounds ...
Type 2 diabetes mellitus (T2DM) is a prevalent yet complex metabolic disorder that has shown a rising incidence over the past few decades. Recent research has identified flavonoids as compounds ...
The following is a summary of “Trending Modalities in Type 2 Diabetes Prevention,” published in the February 2025 issue of Journal of Clinical Endocrinology & Metabolism by Lundgrin & Hatipoglu. A ...
Lexicon's LX9851 targets ACSL5, a liver enzyme involved in fat metabolism that helps moderate fat accumulation and slow down ...
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Both incretin hormones are involved in the physiological regulation of glucose homeostasis ... Avoid excessive alcohol intake (potentiates effects of metformin on lactate). Antagonized by strong ...