Among anti-nuclear antibodies, anti-Sm and anti-RNP antibodies are of the utmost importance in clinical practice. Anti-Sm antibodies are directed against 7 proteins (B/B', D1, D2, D3, E ...
Some assays currently used to detect anti-Sm antibodies, however, fail to differentiate patients with SLE from those with other autoimmune diseases. SmD is considered the most-SLE-specific Sm ...
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