In yeast, free or uncharged tRNA for a particular amino acid activates the kinase GC nonderepressing 2 (GCN2), which then phosphorylates eukaryotic initiation factor (eIF)2α. This signal decreases ...
This achievement represents the completion of the global Sc2.0 project to create the world's first synthetic eukaryotic genome from Saccharomyces cerevisiae (baker's yeast) and a new-to-nature tRNA ...
The tRNA neochromosome is used to house and organise all 275 nuclear tRNA genes from the yeast and will eventually be added to the fully synthetic yeast where the tRNA genes have been removed from the ...
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