Daily treatment with IPL344 for up to three years was safe and slowed ALS progression in a small Phase 2a clinical trial, ...

The Wingless (Wg) signaling pathway is known to be responsible for one of these constrictions, but until now the underlying mechanism regulating this was not known. "We knew that Wingless ...

Wingless shapes the fly intestine Date: March 18, 2025 Source: Institute for Research in Biomedicine (IRB Barcelona) Summary: A study reveals how the Wingless signalling pathway shapes the ...

But how can such simple information reliably activate the range of intricate signalling pathways required to ... in Drosophila melanogaster, the Wingless (Wg) morphogen does more than just trigger ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...

Future research will therefore demonstrate how important the Wnt–β-catenin signalling pathway is for the self-renewal of cancer stem cells. The past two decades have seen a number of cases in ...

This finding not only contributes to our understanding of embryonic development in insects but also expands the effects of the Wingless signalling pathway, which has been highly conserved ...