The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the ...

A USC research team discovered that a single genetic signal may be preventing both hearing and vision cells from repairing themselves. By turning off this signal in mice, they triggered cell growth in ...

Researchers focused on a group of interacting genes called the Hippo pathway, which serve as a 'stop growing' signal that the lab has shown to inhibit cell proliferation in the ear during ...

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Nephronophthisis (NPH) is a recessive cystic kidney disease responsible for 10% to 20% of pediatric end-stage renal disease cases. NPHP1 (nephrocystin 1) is the most frequently implicated among over ...

TGF-β and HIPPO signaling pathways The TGF-β pathway is essential for regulating cell growth, differentiation, and immune responses. It functions as a tumor suppressor by inhibiting cell ...

In the study, first authors Eva Jahanshir and Juan Llamas from the Gnedeva lab focused on a group of interacting genes called the Hippo pathway, which serve as a “stop growing” signal that the lab has ...